The science

Extended release changed the game.

In 2026, Veradermics, Inc. published results from two placebo-controlled trials of its extended-release minoxidil tablet in 1,055 men with pattern hair loss. This is the evidence behind extended-release minoxidil.

+36.4 hairs per cm² in 6 months

Average gain on twice-daily dosing (+28.6 once daily), against +6.6 on placebo.

85% of men said their hair improved

Reported improvement on twice-daily dosing (78.8% once daily), against 35.3% on placebo.

Month 2 results from the first check

Hair growth was already ahead of placebo at month 2, the first time it was measured.

536 men Phase 3 · 45 US sites

Study 304: randomised, double-blind and placebo-controlled, reported 19 October 2026.

Source: Veradermics Study 304 results, SEC filing, 19 Oct 2026

How minoxidil works

At MereBaal, we use extended-release minoxidil, an ingredient that helps slow hair loss and regrow hair.

Minoxidil relaxes blood vessels so blood can flow more easily. In the hair follicle, an enzyme turns it into minoxidil sulfate, its active form. Extended release keeps it in the hair-growth range for longer.

Sources: MedlinePlus; American Academy of Dermatology; Veradermics Study 304 presentation, Oct 2026

Minoxidil

Relaxes blood vessels so blood flows more easily

In the follicle

An enzyme in the hair follicle turns it into its active form

Extended release

Stays in the hair-growth range twice as long as a standard 2.5 mg tablet

Why extended release

More minoxidil, without the spike.

A standard minoxidil tablet releases its whole dose at once: blood levels spike, then fall. Extended release spreads the dose out over the day.

In Veradermics' study, the 8.5 mg extended-release tablet delivered more minoxidil in total than a standard 2.5 mg tablet, with a lower peak. No one on extended release went above 20 ng/mL, the level linked to changes in heart rate. On the standard tablet, 13.3% did.

Source: Veradermics prospectus, Feb 2026, p.110 (single-dose study QSC300720)

Standard 2.5 mg tablet vs extended-release 8.5 mg

Peak level in the blood (ng/mL)

Standard 2.5 mg13.9
Extended release 8.5 mg8.3

Total minoxidil delivered (exposure)

Standard 2.5 mg25.3
Extended release 8.5 mg42.5

People above 20 ng/mL

Standard 2.5 mg13.3%
Extended release 8.5 mg0%
How it compares

Ahead of the treatments men use today.

Average gain in hair count (hairs per cm²) in the published trials of each treatment, as Veradermics set them side by side.

Extended-release minoxidil, twice dailyStudy 304 · 6 months36.4
Extended-release minoxidil, once dailyStudy 304 · 6 months28.6
Finasteride 1 mg tabletPiraccini 2022 · 6 months21.1
Rogaine 5% foamOlsen 2007 · 4 months20.9
Standard oral minoxidil 5 mgPenha 2024 · 6 months14.6
Standard oral minoxidil 5 mgFonseca · 6 months10.0
PlaceboStudy 304 · 6 months6.6

Source: Veradermics Study 304 presentation, 19 Oct 2026, slide 15. These are separate studies, not a head-to-head trial; Veradermics notes that trial designs and participants differ.

82% vs about 20% rated at least moderately improved

In a blinded review of scalp photos presented at EADV 2025, dermatologists rated 82% of men on extended-release minoxidil as at least moderately improved after 4 months. For men on standard oral or topical minoxidil after 6 months, the figure was 14% to 23%.

Source: Veradermics prospectus, Feb 2026, pp.115–118 (Veradermics-sponsored retrospective review)

519 men a second trial, the same result

An earlier Phase 2/3 trial (Study 302) showed +30.3 and +33.0 hairs per cm² in 6 months on once- and twice-daily dosing, against +7.3 on placebo.

Source: Veradermics Study 302 results, SEC filing, 27 Apr 2026

In the news

Science that made headlines.

Extended-release minoxidil and oral minoxidil for hair loss have been covered by international, medical and Pakistani media.

ReutersBloombergThe New York TimesCNBCAssociated PressProPakistaniSTATHealio

Articles report on Veradermics' studies of extended-release minoxidil (VDPHL01) and on oral minoxidil for hair loss. They are not about MereBaal.

All trial results on this page come from Veradermics, Inc. studies of VDPHL01, an extended-release minoxidil 8.5 mg tablet. MereBaal's capsules are compounded separately, in 5 mg and 8 mg, and were not part of these studies.

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